make a reservation

(716) 858-3118

166 Franklin Street, Buffalo, NY 14202

Wednesday – Thursday 12pm to 9pm | Friday 12pm to 10pm | Saturday 5pm to 10pm
Call for catering any day of the week

Welcome to osteria 166

Osteria 166 is one of the hottest restaurants in Western New York. Located in downtown Buffalo (166 Franklin, at the corner of Mohawk,) Osteria 166 is a quick walk across the street from the Buffalo Niagara Convention Center. A short walk down the street from The Hyatt Regency Buffalo and Curtiss Hotels, and other Buffalo hotels and destinations. If you want a place to grab a meal before a show at Shea’s Buffalo Theatre, drinks before a game or concert at Key Center, or a great lunch, head down and we will take care of you.


From the house-cured meats to the 30 bottles of wine priced under $30, Osteria 166 is the perfect place for lunch, dinner or a beverage. Plus, we have our Riserva room for group dinners, parties and can even cater off site. Whether it’s business or pleasure, our food, service and vibe keep people coming back for more.

A place where all are welcome to break bread with friends and leave as family.